Initially, an exploratory analysis was conducted to evaluate normal
distribution (Shapiro–Wilk test) and homogeneity of variance (Levene's
test) of each variable. Variables that presented normal distribution and
homogeneity of variance were analyzed by ANOVA complemented with
Bonferroni post-hoc test. Conversely, for other variables Kruskal–Wallis
complemented with Dunn's test was performed. For body weight and
AGD (PND 21, 28, 35 and 42), repeated measures ANOVA (RMANOVA)
was applied with day as the within-subject factor and treatment as
the between-subject factors. Differences were considered significant if
p b 0.05.