the components or bioactive substances entrapped or encapsulated in the bead(s) are preferably biological or organic substances having a bioactive effect (such as a therapeutic, neutraceutic, cosmetic or biochemical (anabolic or catabolic) activity) upon a cell, tissue, organ or biological substrate (preferably a plant or animal, more preferably a mammal (including a human) cell, tissue or organ) or being a cell, preferably this bioactive substance is selected from the group consisting of an enzyme, a (monoclonal) antibody an antigenic binding portion of a (monoclonal) antibody, an hormone, a vitamin, an active drug (i.e. insulin) or prodrug or a whole cell, such as microalgae, bacteria, fungi including yeast, plant or animal cells or an organelle of a cell, preferably a photosynthetically active cell (microalgae, or plant cells) or a mixture thereof.