Background
Despite declining morbidity and mortality related to malaria globally in the last ten years, malaria remains one of the major public health problems in Myanmar and a significant majorityof malaria cases were caused by Plasmodium falciparum[1,2]. The Greater Mekong Sub-region (GMS) is known as the epicenter of multi-drug resistant P. falciparum, and the presence of artemisinin resistant P. falciparum has been documented in Myanmar along with Cambodia and Vietnam. A gradual decline in the therapeutic efficacy of common artemisinin-based combination therapy [3] and the evidence of artemisinin resistance in the regions of Myanmar bordering Thailand [4], led to the endorsement of Myanmar Artemisinin Resistance Containment (MARC) strategy by World Health Organization. The MARC strategy, implemented by eight implementing partners of the National Malaria Control Program (NMCP) [5], focuses on the mobile migrant populations, with a major emphasis on improving access to vector control measures including personal protection, malaria diagnosis, antimalarial drugs and treatment.
The mobile populations are at an increased risk of exposure to malaria, and it is highly suspected that they are more likely than other groups to carry and spread resistant parasites [6]. In Myanmar a mobile migrant aggregate may comprise workers as well as their families including children, and seasonal migrants may frequently move from one place to the other, with a prolonged interval at times, based on the availability of work and/or security of their livelihoods [7,8]. The nature of their life style hampers with the acquisition of adequate health information and access to quality health care, placing them at a high risk of substandard drug, late diagnosis, inadequate treatment and insufficient follow up, all of which are considered to be contributing factors to the development of drug resistant malaria [9,10]. In addition, the acceptability of and compliance to antimalarial drug treatment may be influenced by different socio-economic factors and/or cultural and belief systems of the specific mobile group, as documented in Lao PDR and Cambodia [11]. There are no data, in our knowledge, describing the nature and distribution of mobile migrant populations along the southern border of Myanmar with Thailand (in Tanintharyi Region), and the structure and conditions of malaria interventions and health care facilities in the region.
พื้นหลังแม้จะปฏิเสธ morbidity และการตายที่เกี่ยวข้องกับโรคมาลาเรียทั่วโลกใน 10 ปี มาลาเรียยังคงเป็นหนึ่งในปัญหาสำคัญในพม่า และกรณีมาลาเรียสำคัญ majorityof ได้เกิดจากเดียม falciparum [1, 2] เรียกว่าจุดศูนย์กลางของ P. falciparum ทนยาหลายอนุภูมิภาคแม่น้ำโขงมากขึ้น (GMS) และได้รับเอกสารของ artemisinin ทน P. falciparum ในพม่ากัมพูชาและเวียดนาม ค่อย ๆ ปรับลดประสิทธิภาพยาบำบัด artemisinin โดยรวมทั่วไป [3] และหลักฐานของความต้านทานของ artemisinin ในภูมิภาคของพม่าที่ล้อมรอบประเทศไทย [4], นำไปสลักหลังกลยุทธ์ต้านทานพม่า Artemisinin บรรจุ (มาร์ค) โดยองค์การอนามัยโลก กลยุทธ์มาร์ค ดำเนินการ โดยพันธมิตรแปดนำไปใช้ของชาติมาลาเรียควบคุมโปรแกรม (NMCP) [5], เน้นประชากรข้ามชาติเคลื่อน โดยเน้นหลักในการปรับปรุงถึงเวกเตอร์มาตรการควบคุมป้องกันส่วนบุคคล ตรวจหาเชื้อมาลาเรีย ยาป้องกันมาเลเรีย และรักษาThe mobile populations are at an increased risk of exposure to malaria, and it is highly suspected that they are more likely than other groups to carry and spread resistant parasites [6]. In Myanmar a mobile migrant aggregate may comprise workers as well as their families including children, and seasonal migrants may frequently move from one place to the other, with a prolonged interval at times, based on the availability of work and/or security of their livelihoods [7,8]. The nature of their life style hampers with the acquisition of adequate health information and access to quality health care, placing them at a high risk of substandard drug, late diagnosis, inadequate treatment and insufficient follow up, all of which are considered to be contributing factors to the development of drug resistant malaria [9,10]. In addition, the acceptability of and compliance to antimalarial drug treatment may be influenced by different socio-economic factors and/or cultural and belief systems of the specific mobile group, as documented in Lao PDR and Cambodia [11]. There are no data, in our knowledge, describing the nature and distribution of mobile migrant populations along the southern border of Myanmar with Thailand (in Tanintharyi Region), and the structure and conditions of malaria interventions and health care facilities in the region.
การแปล กรุณารอสักครู่..
