• Nerve fibers travel in bundles (peripheral nerves) to the spinal cord
• Two major pathways in the spinal cord:
– Medial lemniscal pathway consists of large fibers that carry
proprioceptive and touch information
– Spinothalamic pathway consists of smaller fibers that carry
temperature and pain information
– These cross over to the opposite side of the body and synapse in
the thalamus, and then on to the Somatosensory cortex, or SA1