The vaccinated trout displayed strong protection,
similar levels to those previously described for fish that were
individually vaccinated with alginate-encapsulated plasmid [29].
The cumulative mortality was similar in the replicate experiments
performed, despite the possible variability in feed uptake over the 3
days of vaccination. Interestingly, very low levels of mortality were
recorded during the first 10e12 days in all the vaccinated fish,
suggesting an antiviral effect induced by the activation of IFN and
other genes involved in immune responses.