The colostrum, but not the placebo group, showed a mean reduction in symptom score, and an improvement in histological score.[23] In an 8-week double-blind randomised study, Xilei-san, a traditional Chinese herbal medicine with anti-inflammatory properties, was compared with dexamethasone enemas in 35 subjects with mild-to-moderate active ulcerative proctitis. Subjects were followed up for 12 weeks.