Methods: We developed a stable aqueous solution of 15% L-ascorbic acid (vitamin C) and 1% -tocopherol
(vitamin E). We applied antioxidant or vehicle solutions to pig skin daily for 4 days. We irradiated (1-5minimal
erythema dose) control- and antioxidant-treated skin using a solar simulator with a 295-nm band-pass filter. On
day 5, we measured antioxidant protection factor, erythema, sunburn cells, and thymine dimers.