In 2012, the CDC received reports of 1,778 cases of
acute HCV infection,1 which suggests that the actual
number of acute cases was 21,869, since each reported
case is estimated to represent 12.3 actual cases.6 The
CDC also documented a 75% increase in new HCV
infections between 2010 and 2012 and linked the increase
to rising injection drug use, primarily among white adolescents and young adults who reside in nonurban
settings.