Conclusion and Perspectives
Detection of GM in patient serum by sandwich ELISA is the most reliable and non-invasive approach for the detection of IA in intensive care units. However, false-positive results have been reported at the rate of 8–14% for this assay. We therefore conclude that, although GM detection in the serum is a useful method for early diagnosis of IA, the GM levels should be interpreted with results from other examinations such as radiology. More studies are necessary to introduce a novel kit with higher sensitivity and minimal false-positive results for precise diagnosis of IA.