Since, their discovery, carbon nanotubes (CNTs) have been eminent members of the nanomaterial family. Because of their unique physical, chemical and mechanical properties, they are widely predicted and regarded as new potential materials to bring enormous benefits in cell biology studies1. Also, an increasing number of reports have studied the toxicological impact and safety profile of carbon nanomaterial on both plant2 and mammalian cells, indicating that a high degree of CNT functionalization leads to a dramatic reduction in toxic effects3.