Oral squamous cell carcinoma (OSCC) accounts for more than
90% of all oral cancers and is the sixth most common type
of cancer in the world [1]. About 275 000 new cases of OSCC
are diagnosed each year globally [2]. The 5-year survival rate
of OSCC has not improved much over the past 2 decades [3].
In China, evidence has shown that the risk of morbidity for
OSCC patients is still high and that OSCC tends to occur among
younger patients [4]. Thus, much research effort is needed to
address this public health threat worldwide.