Novel hydrogels were prepared from carboxymethyl cellulose(CMC) sodium salt by crosslinking with
polyethylene glycoldiglycidyl ether(PEGDE).The detailed structures of the hydrogels were determined
via FTIR and solid-stat eNMR spectroscopic analyses.Increasing the feed ratio of PEGDE to CMC in the
reaction mixture led to an increase in the crosslinking degree, which enhanced the physical strength
of the hydrogels.The hydrogels exhibited enzyme degradability,and after 3 days of incubation with
cellulase, 62–28wt% of the CMC in the hydrogel was degraded under the conditions employed in this
study.Inaddition, the hydrogels exhibited protein adsorption and release abilities,and the amounts of
proteins adsorbed on the hydrogels and the release profile of the proteins depended on the protein sizes
and crosslinking degree of the hydrogels.