Angucyclinones are a subclass of angucyclines, which are defined as
microbial quinone natural products related to tetracyclines and
anthracyclines and bearing, as characteristic structural feature, a
tetracyclic benz[a]anthracene ring system assembled in an angular
manner.This structural moiety is biosynthetically derived from a
decaketide chain formed via the polyketide biosynthetic pathway.
The term ‘angucycline’ includes molecules with hydrolysable sugar
moieties, whereas ‘angucyclinone’ refers to a sugarless compound or a
compound with a C-glycosidic linked sugar moiety.Angucyclines
are isolated from the fermentation broth of actinomycetes, mostly
from the genus Streptomyces, but also from Actinomadura, Nocardia
and Streptosporangium genera