cause bone marrow suppression in a number of
species, including humans, dogs, cats, storks, vultures,
vipers, and sand tiger sharks.4-7 Furthermore,
subtherapeutic dosing may also lead to
resistance in target and nontarget pathogens. Individual
dosing would minimize the potential
for these side effects in nontarget fish. However,
the individual treatment of fish using injections
or oral dosing is impractical for management of
epizootic diseases in large collections. Therefore,