When CHM1 culture suspension was sprayed on plant leaves, it protected maize (Zea mays) against infection by Bipolaris maydis and horsebean (Vicia faba) against infection by R. solani with a mean control efficacy of 70.22 and 62.79%, respectively. The culture suspension of CHM1, drenched around the root of rice and cole (Brassica napus), promoted seedling growth. The data here showed that Bacillus sp. CHM1 could be a potential agent to protect maize, horsebean, cole and rice (Oryza sativa) plants from infection by pathogenic fungi in vivo and had properties as a plant growth-promoting endophytic bacterium (PGPE).