After 6 h of pre-incubation with BL bacterial extract
(0.3% and 1%) followed by neurone stimulation by capsaicin,
a significant decrease in CGRP release was observed
(p < 0.01) (37.5 ± 12.2 pg ⁄ ml after 0.3% of BL compared
to 91.0 ± 16.4 pg ⁄ ml in the control group treated with capsaicine alone (decrease of 36%) and 32.6 ± 5.3 pg ⁄ ml
after 1% of BL compared with 91.0 ± 16.4 pg ⁄ ml in the
control group (decrease of 41%), p < 0.01) (Fig. 2).