We have used a novel MFC for live-imaging the filtration of cancer cells from whole mouse blood in order to optimize filtration and washing steps.
Using real-time monitoring with the MFC, we can:
• Increase the purity of trapped cancer cells without compromising
recovery
• Explore the use of back pulses to further reduce contamination
• Improve the specificity of simple, rapid filtration
By improving the purity of cells isolated using a label-free method, we can facilitate easier downstream analysis.