Tissue engineering has been a promising field of
research, offering hope for bridging the gap between organ
shortage and transplantation needs. However, building threedimensional (3D) vascularized organs remains the main
technological barrier to be overcome. Organ printing, which is
defined as computer-aided additive biofabrication of 3D cellular
tissue constructs, has shed light on advancing this field into a new
era. Organ printing takes advantage of rapid prototyping (RP)
technology to print cells, biomaterials, and cell-laden biomaterials
individually or in tandem, layer by layer, directly creating 3D
tissue-like structures. Here, we overview RP-based bioprinting
approaches and discuss the current challenges and trends towards
fabricating living organs for transplant in the near future.