The current paper provides some additional advanced details of how these teaching methods can be applied specifically to laboratory methods used in each of the various steps involved in e-nose analytical procedures used in diagnostic clinical (chemical) laboratories. E-nose laboratory methods and analytical procedures are described here with specific recommendations of key factors that improve the performance and effectiveness of instrument operations when applied at each step in analytical processes. Incorporation of these key factors within the training program consequently should improve the quality of training received by laboratory staff and ultimately result in more effective and higher quality results obtained from e-nose analyses