provides an additional rationale for the first use of a
boosted PI when adherence may be a problem. However, NNRTI-based regimens may have
lower pill burdens and provide greater convenience (particularly the fixed-dose regimen of
tenofovir/emtricitabine/efavirenz), and possibly improved lipid profiles, when compared to PIbased
regimens. Although there is less experience with INSTI-based regimens, studies to date
show similar virologic outcomes with raltegravir when compared to efavirenz, when either is
combined with tenofovir and emtricitabine, over 96 weeks of observation (37).
provides an additional rationale for the first use of aboosted PI when adherence may be a problem. However, NNRTI-based regimens may havelower pill burdens and provide greater convenience (particularly the fixed-dose regimen oftenofovir/emtricitabine/efavirenz), and possibly improved lipid profiles, when compared to PIbasedregimens. Although there is less experience with INSTI-based regimens, studies to date show similar virologic outcomes with raltegravir when compared to efavirenz, when either iscombined with tenofovir and emtricitabine, over 96 weeks of observation (37).
การแปล กรุณารอสักครู่..
