Fish sauce contains beneficial antioxidants and ACE inhibitors,and fish sauce prepared from squid contains high concentrations of taurine, which facilitates recovery from fatigue (Michihata et al., 2000; Taniguchi et al., 2009). Taurine contents in untreated fish sauce and in treated first fractions were 720 ± 10 and 700 ± 1 mg/100 mL, respectively. DPPH radical scavenging activity was also determined using gallic acid as a standard radical scavenger,and did not differ between untreated fish sauce and first fractions(0.96 ± 0.08 vs. 0.96 ± 0.08 lmol/mL, respectively). Moreover,ACE IC50 values did not differ between untreated fish sauce and first fractions (9.5 ± 0.7 vs. 9.8 ± 0.9 lL/mL, respectively). These major functionalities remained in all subsequent fractions, confirming that CR11 did not remove organic compounds.