Prostate weights of rats in the BPH group (1.94 ± 0.07 g) showed a significant increase compared to those of rats in the control group (0.84 ± 0.03 g; P < 0.001) (Table 3). KH053 treated groups (1.63 ± 0.06 g, P < 0.01) showed sig- nificant decreases in prostate weights compared with those of the BPH group. Prostate weights in the finasteride group were also decreased markedly compared with the BPH group. These results were similar to those for the KH053-treated group.