A total of 2137 patients who were on dialysis for at least 3 months, with PTH < 500 ng/L were retrieved from the REIN registry – Region of Lorraine between 1st December, 2009 and 31st May, 2012. Among them, 305 patients were included in the EPHEYL study: 86% with an incident PTH ≥500 ng/L (n = 261), 14% with an initiation of cinacalcet (n = 44), and 0% with a first-line parathyroidectomy (Figure 1).