The mixed solvents (CO2ethanolwater) containing either 6% or 10% water, which are equivalent to a mixture of 80% CO2 and 20% ethanol/water (70:30) or 80% CO2 and 20% ethanol/water (50/50), respectively, formed two layers [9] that may have promoted instability, resulting in large deviations of the extraction yield (Fig. 7). In view of this, this study did not consider the extraction using 10% water, thus providing only a single extraction curve for this condition.