CJ is framed for the murder of officer Ralph Pendelbury by Tenpenny and Pulaski when he arives in Los Santos.
Grove Street starts to reconquer its territory and pushes back the distribution of drugs.
Cesar Vialpando finds out about Big Smoke and Ryders betrayal and tells CJ. This causes CJ to be late for a shoot-out with the Ballas.
Sweet is badly wounded and gets arrested.
CJ is kidnapped by Tenpenny and Pulaski and is forced by them to do several jobs.
CJ meets Cesars cousin Catalina and together they rob a bank, liquor store, tank station and a betting shop.
CJ meets The Truth
CJ meets Wu Zi Mu, a member of the Triads
Catalina meets Claude and they give CJ the deed of a run-down garage in San Fierro in excange for winning a race, before leaving San Andreas.
Catalina says they're heading for Liberty City, although they won't arrive there until 2001.
CJ infiltrates the Loco Syndicate and kills Jizzy B., T-Bone Mendez and Ryder.
CJ meets Mike Toreno, although he thought he killed him. Toreno reveals he is not a member of the Loco Syndicate, but of a unspecified government agency. Toreno promises he will get Sweet out of prison if CJ helps him with a few jobs.
The Four Dragons Casino comes under management of the Triads.
Officer Hernandez realises things have gotten out of hand and he reports the crimes of C.R.A.S.H.. Tenpenny finds out and uses CJ to retrieve the file so his crimes won't come out. He hits Hernandez unconscious and leaves Pulaski to deal with CJ and Hernandez. Pulaski forces CJ to dig his and Hernandez' grave. When Pulaski wants to shoot CJ, Hernandez manage to stop him, but gets hit himself and dies. Pulaski tries to escape, but CJ goes in pursuit and kills him.
Toreno keeps his promise and Sweet is released from prison. He and CJ start reconquering Los Sanots.
Tenpenny is trialled but accused not guilty, causing riots to start in the ghetto's of Los Santos.
CJ breaks in Big Smoke's Crack Palace and kills Big Smoke. Tenpenny shows up, who forces CJ to fill a suitcase with money.
He tries to kill CJ afterwards, but CJ tricks Tenpenny into thinking Sweet is behind him and manage to evade the bullet.
Tenpenny drives away in a Fire Truck. CJ and Sweet follow him, until Tenpenny drives of the edge of a bridge and dies in the crash.