As a way to attract and promote a good investment especially the poor countries, the budget in the infrastructure development is limited. Apply investment to go through many procedures and take a long time, may make special economic zone not succeed and no sustainability. All area created depending on the conditions and environment in many aspects. Therefore, determining the location and target for the development of special economic zone is important very much for development opportunities in special economic zone of Lao PDR there are several factors that support and challenge.