Studies on nitric oxide (NO) and heme oxygenase-1 (HO-1)-
mediated production of carbon monoxide (CO) have highlighted
the possible crosstalk between gaseous signaling molecules in
biology. Further evidence suggested that another novel endogenous
gasotransmitter, hydrogen sulfide (H2S), also plays important
physiological functions alongside NO and CO in animal systems
(Wang, 2003). For example, anti-inflammatory, metabolic