The
Food and Drug Administration has established a maximum tolerance
level of 100 mg/kg for histamine in flesh (FDA, 1990); EFSA has recently
established a daily maximum intake of 50 mg of histamine, and 600 mg
of tyramine can be considered safe for healthy individuals, although such
limitsmay be drastically reduced in case of reported intolerance or use of
monoamine oxidase inhibitor drugs (EFSA, 2011).