tPreviously, studies have demonstrated that topical application of simvastatin can promote wound healingin diabetic mice via augmentation of angiogenesis and lymphangiogenesis. This study aimed to formulateand characterize simvastatin in alginate-based composite film wound dressings. Biopolymers used forcomposite films were sodium alginate blended with pectin or gelatin. The films were prepared andcharacterized based on their physical properties, surface morphology, mechanical strength and rheology.Then, in vitro drug releases from the films were investigated and, finally, the cell viability assay wasperformed to assess the cytotoxicity profile. From the pre-formulation studies, alginate/pectin compositefilm showed to possess desirable wound dressing properties and superior mechanical properties. Thein vitro drug release profile revealed that alginate/pectin film produced a controlled release drug profile,and cell viability assay showed that the film was non-toxic. In summary, alginate/pectin composite filmis suitable to be formulated with simvastatin as a potential wound dressing.