5.2. AnalgesicactivityThe mostfrequ

5.2. Analgesicactivity
The mostfrequentlycitedreasonthatpeopleturntocomple-
mentary andalternativemedicineispainrelief(Astin, 1998).
The aqueoussecondarytuberextractof H. procumbens (50–800
mg/kg) producedsignificantanalgesiceffectsagainstthermally
(hot-plate) andchemically(aceticacid)inducednociceptive
pain stimuliinmice(Mahomed andOjewole,2005). Intra-
peritoneal administrationofanaqueousextractof H. procumbens
at400mg/kgtomicesignificantlyreducedthenumberofwrithing
reactions(Ahmedetal.,2005) and Uchidaetal.(2008) reported
that H. procumbens extractexertedsignificantantinociceptive
effectsintheformalintestinmice.Administeredatadoseof
30–300mg/kg,theextractreducedthetimesoflicking/bitingin
boththefirstandsecondphasesofformalininjectioninmiceina
dose-dependentmanner.Thesignificantincreaseinthecontentof
nitrites/nitrates(NOx)inthemousespinalcordcausedbyformalin
injectionwassignificantlyattenuatedby H. procumbens extract.
Additionally,itwasdeterminedthattheopioidergicsystem
seemstobeinvolvedintheantinociceptiveeffectof H.procumbens
(Uchidaetal.,2008).

ผลลัพธ์ (ไทย) 1:

5.2 analgesicactivity
mostfrequentlycitedreasonthatpeopleturntocomple-
mentary andalternativemedicineispainrelief (Astin, 1998).
aqueoussecondarytuberextractof ชั่วโมง procumbens (
50-800 mg / kg) producedsignificantanalgesiceffectsagainstthermally
(ร้อนแผ่น) andchemically (aceticacid) inducednociceptive
ปวด stimuliinmice (andojewole mahomed, 2005) ภายใน
administrationofanaqueousextractof ชั่วโมงทางช่องท้อง procumbens

at400mg/kgtomicesignificantlyreducedthenumberofwrithing ปฏิกิริยา (ahmedetal. , 2005) และ uchidaetal. (2008) รายงานว่า h
procumbens extractexertedsignificantantinociceptive
effectsintheformalintestinmice.administeredatadoseof
30–300mg/kg,theextractreducedthetimesoflicking/bitingin
boththefirstandsecondphasesofformalininjectioninmiceina
dose-dependentmanner.thesignificantincreaseinthecontentof
nitrites/nitrates(nox)inthemousespinalcordcausedbyformalin
injectionwassignificantlyattenuatedby เอช procumbens extract.
additionally,itwasdeterminedthattheopioidergicsystem
seemstobeinvolvedintheantinociceptiveeffectof h.procumbens
(uchidaetal. , 2008)

ผลลัพธ์ (ไทย) 2:

5.2. Analgesicactivity
mostfrequentlycitedreasonthatpeopleturntocomple-
mentary andalternativemedicineispainrelief(Astin, 1998).
procumbens aqueoussecondarytuberextractof H. (50–800
mg/kg) producedsignificantanalgesiceffectsagainstthermally
(hot-plate) andchemically (aceticacid) inducednociceptive
stimuliinmice (Mahomed andOjewole, 2005) อาการปวด อินทรา-
peritoneal administrationofanaqueousextractof H. procumbens
at400mg/kgtomicesignificantlyreducedthenumberofwrithing
reactions(Ahmedetal.,2005) และ Uchidaetal(2008) รายงาน
ที่ H. procumbens extractexertedsignificantantinociceptive
effectsintheformalintestinmiceAdministeredatadoseof
30–300mg/kg, theextractreducedthetimesoflicking/bitingin
boththefirstandsecondphasesofformalininjectioninmiceina
dependentmanner ยาThesignificantincreaseinthecontentof
nitrates nitrites (โรงแรมน็อกซ์) inthemousespinalcordcausedbyformalin
injectionwassignificantlyattenuatedby H. procumbens สารสกัด
นอกจากนี้ itwasdeterminedthattheopioidergicsystem
seemstobeinvolvedintheantinociceptiveeffectof H.procumbens
(Uchidaetal.,2008)

ผลลัพธ์ (ไทย) 3:

5.2 . analgesicactivity
ที่ mostfrequentlycitedreasonthatpeopleturntocomple -
mentary andalternativemedicineispainrelief ( astin , 1998 )..
ที่ aqueoussecondarytuberextractof H procumbens ( 50 - 800
มก./กก.) producedsignificantanalgesiceffectsagainstthermally
( Hot - แผ่น) andchemically ( aceticacid ) inducednociceptive
ซึ่งจะช่วยลดความเจ็บปวด stimuliinmice ( mahomed andojewole, 2005 ) ภายใน -
peritoneal administrationofanaqueousextractof H procumbens
ที่ 400 มก./ kgtomicesignificantlyreducedthenumberofwrithing
เกิดปฏิกิริยา( ahmedetal . , 2005 )และ uchidaetal .( 2008 )รายงานว่า
ที่ H procumbens extractexertedsignificantantinociceptive
effectsintheformalintestinmice.Administeredatadoseof
30–300mg/kg,theextractreducedtheboththefirstandsecondphasesofformalininjectioninmiceina
dose-dependentmanner.Thesignificantincreaseinthecontentof
nitrites/nitra H procumbens ดึง.
นอกจากนี้, itwasdeterminedthattheopioidergicsystem

procumbens seemstobeinvolvedintheantinociceptiveeffectof H .( uchidaetal . , 2008 ).