The major risk of mixing statins and grapefruit is increasing the side effects of the drugs. The FDA reports that this could put you at risk for muscle breakdown, liver damage and kidney failure.
Statins also carry other risks, such as digestive problems, increased blood sugar and neurological side effects, including confusion and memory loss, according to Mayo Clinic. Women and people over 65 years old are at a higher risk of developing side effects from statins.