Vitamin C administration significantly hampers
endurance capacity in rats and does not improve
V˙ O2max associated with training in rats and in humans
Training significantly (P 0.004) increased the maximal
running time in rats (Table 2), from 99.2 6.6 min in untrained
rats to 284.3 105.9 min in trained rats. However, this increase
was significantly (P 0.014) prevented by daily supplementation
with vitamin C. In the supplemented animals, the running
timeincreased only 26.5%, from 101.29.7 minto 128.044.7
min. Although we found a dramatic effect of vitamin C on endurance
time in animals, we did not find the same effect on
V˙O2max. We performed a V˙O2max test before and after the
training period (6 wk) and found a significant (P 0.05) increase