4.1. Results of the systematic review
4.1.1. Study characteristics
A detailed description of each of the 7 included studies is provided in
Table 2. According to this table, 1 of the studies was a randomized
controlled study, but no double blinding for which the methodological
quality was level B. The remaining studies were self-controlled clinical
trials, and similarly, the methodological quality of those studies was
fair (level B) [26]. A total of 486 intensive care patients from samples
ranging from 9 to 262 patients were included in these studies.