All children exposed to B anthracis spores should receive at least 60 days of antimicrobial prophylaxis with the most effective agents, even if these agents are associated with increased side effects compared with antimicrobials more often used in children.
Oral ciprofloxacin and doxycycline are preferred, or if the strain is susceptible to penicillin, amoxicillin should be used.
In addition to antimicrobials, all exposed children aged 6 weeks and older should receive 3 doses of anthrax vaccine adsorbed (AVA) at 0, 2, and 4 weeks. Children younger than 6 weeks should immediately begin antimicrobial prophylaxis but delay starting the vaccine series until 6 weeks of age. During an event, immunization with AVA should be given priority over routine childhood vaccinations -- they should not be administered at the same time. Routine vaccinations can resume 4 weeks after the last shot of AVA.
All children exposed to B anthracis spores should receive at least 60 days of antimicrobial prophylaxis with the most effective agents, even if these agents are associated with increased side effects compared with antimicrobials more often used in children.
Oral ciprofloxacin and doxycycline are preferred, or if the strain is susceptible to penicillin, amoxicillin should be used.
In addition to antimicrobials, all exposed children aged 6 weeks and older should receive 3 doses of anthrax vaccine adsorbed (AVA) at 0, 2, and 4 weeks. Children younger than 6 weeks should immediately begin antimicrobial prophylaxis but delay starting the vaccine series until 6 weeks of age. During an event, immunization with AVA should be given priority over routine childhood vaccinations -- they should not be administered at the same time. Routine vaccinations can resume 4 weeks after the last shot of AVA.
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