Enzymatic pre-bleaching is one of the promising alternatives for eliminating/reducing chlorine-based chemicals in the pulp bleaching process. Enzymes of the hemicellulolytic type, particularly xylan attacking enzymes, xylanases, are now used commercially in the mills for pulp treatment and subsequent incorporation into bleach sequences. A variety of bleaching benefits have been realized. These include reducing AOX discharges; increasing the brightness ceiling; decreasing the cost of bleaching chemicals; and debottlenecking mills limited by chlorine dioxide generator capacity. Lignin-oxidizing enzymes are found to be more effective for bleaching pulp because they attack lignin directly. An overview of developments in the application of xylanase enzymes and lignin-oxidizing enzymes in pulp bleaching is presented.