Innate immunity establishes the first line of defense against
pathogenic microorganisms. The host senses pathogenic microorganisms
invasion by recognition of pathogen-associated molecular
patterns (PAMP) with pattern recognition receptors (PRR),
including Toll-like receptor (TLR), RIG-I-like receptors (RLRs) and
NOD-like receptors (NLRs) [1]. RLRs mainly sense cytoplasmic viral
RNA and play a key role in regulating the inflammatory response
against infectious viruses [