scolex region were described for the effects of Cassia alata leaf
extract on the tapeworm Hymenolepis diminuta.
20
Albendazole and its related benzimidazoles are established to
enter the helminth body by passive diffusion through the tegument
in tapeworms, where they directly cause disruption of the tegumental
and muscle layers by binding specifically to b-tubulins,
thereby, inhibiting assembly and functioning of the cellular motor
proteins.21 The tegument or cuticle is the fundamental interface of
the helminth body with its environment, and responsible for selective
absorption of nutrients, secretory activities and sensory
perception, rendering it specifically susceptible to anthelmintic
agents. Consequently, the tegument is the primary target of
anthelmintic agents.
Formation of numerous b