In this work, we demonstrated a conceptual bio-solar panel by integrating small-scale biological solar cells in an array format, which is self-sustainable and scalable for the field applications. Significant performance enhancement was achieved by maximizing bacterial photoelectrochemical activities in well-controlled micro-chambers while self-sustainability was improved with fundamental device architectural modification. This work could result in barrier-transcending advancements in bio-solar cells that could facilitate higher power/voltage generation with self-sustainability, releasing bio-solar cell technology from its restriction to research settings, and translating it to practical applications in real-world.