Currently, ultra-high resolution and accuracy mass spectrometry such as Fourier transform ion cyclotron resonance mass
spectrometry (FT-ICR MS) allows for the identification of complex organic mixtures without the need for any prior extraction or separation steps. FT-ICR MS is applied in all the ‘‘omics’’ sciences (i.e. metabolomics, proteomics, and petroleomics), thus enabling molecular-level analyses of complex mixtures (Beens & Brinkman, 2000; Klein, Kim, Rodgers, & Marshall, 2006).