a chemical toxicity can be measured in two basic ways: (1) chronic toxicity and (2) acute toxicity, Chronic toxicity refers to dose of a chemical that, while safe if ingested once, can cause harm if ingested over a long period of time. chronic toxicity effects Example Dental fluorosis, The effect of long term fluoride exposure on bone is still controversial
Acute contrast, refers to the dose of a chemical that, if ingested in ane sitting, cause immediate Acute toxic effects Example Gastric disturbance, Nausea, vomiting ,Death