The concentrations of fatty acids in serum have been reported to be altered in various diseases, including diabetes [5] and depressive disorder [6]. In particular, PUFA levels have been found to be correlated with symptoms or severity of neurological disorders, such as Alzheimer’s-type dementia [7] and schizophrenia [8]. Additionally, the beneficial effects of fatty acid supplementation have been studied in patients with neurological disorders, such as depression
[9,10], bipolar disorders [11], and chronic epilepsy [12], in several small clinical trials. Therefore, determination of the levels of fatty acids in biosamples such as serum or plasma may be relevant for the diagnosis of psychiatric diseases.
The concentrations of fatty acids in serum have been reported to be altered in various diseases, including diabetes [5] and depressive disorder [6]. In particular, PUFA levels have been found to be correlated with symptoms or severity of neurological disorders, such as Alzheimer’s-type dementia [7] and schizophrenia [8]. Additionally, the beneficial effects of fatty acid supplementation have been studied in patients with neurological disorders, such as depression[9,10], bipolar disorders [11], and chronic epilepsy [12], in several small clinical trials. Therefore, determination of the levels of fatty acids in biosamples such as serum or plasma may be relevant for the diagnosis of psychiatric diseases.
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