Hepatocellular carcinoma is a one of the most common cancer in the world and the third cause of cancer-related death.
The recommended screening test for patients are the detection of serum α-fetoprotein (AFP) levels and an abdominal ultrasound every 6 months to detect HCC.
To inform stage of the diasease, we investigate the alpha fetoprotein (AFP) which is a major HCC biomarker by using surface Plasmon resonance (SPR) technique.
SPR is an optical biosensor, nanoscale detectable and highly sensitive technique which is suitable for an early detection application.
The interaction of anti-AFP antibody and AFP antigen was created via sandwich assay on carboxy dextran sensor surface.