Disadvantages of HFCWO have been largely overshadowed by its reported advantages.
However, when compared with CPT, the perceived disadvantages of HFCWO may be inherently related to longer duration of therapy sessions, unknown cost benefit, and portability of the equipment (as a larger device).
Overall, little evidence supports the idea that oscillation such as HFCWO is more effective than CPT among patients with cystic fibrosis.