4. Conclusions
In recent years, only a few reports proposed methods for the
analysis of NSAIDs in pig serum. To our best of knowledge,this work
is the first report using online eluent-switching technique coupled
anion-exchange liquid chromatography–ion trap mass spectrometry
for the extraction, separation, and analysis of nine NSAIDs in
incurred pig serum specimens. The present method for the determination
of NSAIDs in pig serum is accurate, precise, sensitive,
and convenient. In addition,the newly developed eluent-switching
online sample cleanup procedure is simple and efficient.