Sixty-four
weaned pigs (6.3 ± 0.2 kg BW, and 21 d old) were housed
in individual pens in disease containment chambers for
15 d: 4 d before and 11 d after the first inoculation (d
0). Treatments were in a 2 × 4 factorial arrangement:
with or without an F-18 E. coli challenge (toxins: heatlabile
toxin, heat-stable toxin b, and Shiga-like toxin 2;
1010 cfu/3 mL oral dose; daily for 3 d from d 0) and 4
diets [a nursery basal diet (CON) or 10 ppm of capsicum
oleoresin, garlic botanical, or turmeric oleoresin].
The growth performance was measured on d 0 to 5, 5 to
On d 5 and 11, half of the pigs
were euthanized to measure villi height and crypt depth
of the small intestine and macrophage and neutrophil
number in the ileum. The E. coli infection increased
(P < 0.05) diarrhea score, frequency of diarrhea, white
blood cell counts, serum TNF-α and haptoglobin, and
ileal macrophages and neutrophils but reduced (P <
0.05) villi height and the ratio of villi height to crypt
depth of the small intestine on d 5. In the challenged
group, feeding plant extracts reduced (P < 0.05) average
diarrhea score from d 0 to 2 and d 6 to 11 and frequency
of diarrhea and decreased (P < 0.05) TNF-α and
haptoglobin on d 5, white blood cell counts and neutrophils
on d 11, and ileal macrophages and neutrophils
on d 5. Feeding plant extracts increased (P < 0.05) ileal
villi height on d 5 but did not affect growth performance
compared with the CON. In the sham group, feeding
plant extract also reduced (P < 0.05) diarrhea score,
frequency of diarrhea, and ileal macrophages compared
with the CON. In conclusion, the 3 plant extracts tested
reduced diarrhea and inflammation caused by E. coli
infection, which may be beneficial to pig health.
Sixty-fourweaned pigs (6.3 ± 0.2 kg BW, and 21 d old) were housedin individual pens in disease containment chambers for15 d: 4 d before and 11 d after the first inoculation (d0). Treatments were in a 2 × 4 factorial arrangement:with or without an F-18 E. coli challenge (toxins: heatlabiletoxin, heat-stable toxin b, and Shiga-like toxin 2;1010 cfu/3 mL oral dose; daily for 3 d from d 0) and 4diets [a nursery basal diet (CON) or 10 ppm of capsicumoleoresin, garlic botanical, or turmeric oleoresin].The growth performance was measured on d 0 to 5, 5 toOn d 5 and 11, half of the pigswere euthanized to measure villi height and crypt depthof the small intestine and macrophage and neutrophilnumber in the ileum. The E. coli infection increased(P < 0.05) diarrhea score, frequency of diarrhea, whiteblood cell counts, serum TNF-α and haptoglobin, andileal macrophages and neutrophils but reduced (P <0.05) villi height and the ratio of villi height to cryptdepth of the small intestine on d 5. In the challengedgroup, feeding plant extracts reduced (P < 0.05) averagediarrhea score from d 0 to 2 and d 6 to 11 and frequencyof diarrhea and decreased (P < 0.05) TNF-α andhaptoglobin on d 5, white blood cell counts and neutrophilson d 11, and ileal macrophages and neutrophilson d 5. Feeding plant extracts increased (P < 0.05) ilealvilli height on d 5 but did not affect growth performanceเปรียบเทียบกับคอน ในกลุ่มซัมซุยโป อาหารโรงงานสกัดยัง ลดลง (P < 0.05) ท้องเสียคะแนนความถี่ของโรคท้องร่วง และบังเอิญ ileal เปรียบเทียบมีแอร์ด้วย เบียดเบียน สารสกัดจากพืช 3 การทดสอบโรคท้องร่วงลดลงและการอักเสบที่เกิดจาก E. coliติดเชื้อ ซึ่งอาจเป็นประโยชน์ต่อสุขภาพหมู
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