MethodsDesignIn this randomized controlled trial, 46 CRC patients(stages 1–3) were randomized to either (i) a 12-week, home-based moderate-intensity PA program(PA group) or (ii) a contact control condition (con-trol group). Assessments were conducted at baseline,3, 6, and 12 months. The Institutional Review Boardsat The Miriam Hospital and the Women and InfantsHospital approved the study. Study enrollment oc-curred between December 2005 and February 2009