The present study was to evaluate the antimicrobial properties of solvent extracts from leaf and stem of
Wedelia chinensis. The ethylacetate, acetone, methanol and hexane extract of medicinal plant were evaluated
against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli by using
well diffusion assay. The leaf extract showed maximum antimicrobial activity against Bacillus subtilis (16.4±0.7) and lowest
activity against Escherichia coli (9.4±0.6) compared with ciprofloxacin. The stem extract showed maximum antimicrobial activity
against Staphylococcus aureus (15.3±0.8) and lowest activity against Pseudomonas aeruginosa (6.3±0.5) compared with ciprofloxacin
(10mcg,). The antimicrobial activity could be confirmed in most species used in traditional medicine in South India. Nevertheless,
traditional knowledge might provide some leads to elucidate potential candidates for future development of new antibiotic agent