ABSTRACT
The domesticated silkworm, Bombyx mori Linn., a lepidopteran molecular model and an important
economic insect that are emerging as an ideal molecular genetic resource for solving a broad range of
biological problems. The silkworm, B. mori produces massive amount of silk proteins during the final
stage of larval development. These proteins are stored in the middle silk gland and they are discharged
through the anterior duct and spinneret, at the end of the fifth instar. Two kinds of silk proteins have been
distinguished as major components of silk cocoons, the first being fibroin, a fibrous protein composed of
heavy (H) chain, Light (L) chain and glycoprotein linked by disulfide bonds and the second being sericin a
natural macromolecular protein, serving as an adhesive to unite fibroin for making silk cocoons of
silkworm, B. mori. Recently, silkworm is being used as biofactory for the production of useful protein
using the silk gland, which has promoted the technological development in sericulture. With the above
background silkworm can be classified as a value added biomaterial for medical application, application
of silk protein fibroin and sericin as a biomaterial and other seri-byproducts. The present paper overviews
some important studies carried out on sericin and fibroin of silkworm, Bombyx mori Linn
ABSTRACT
The domesticated silkworm, Bombyx mori Linn., a lepidopteran molecular model and an important
economic insect that are emerging as an ideal molecular genetic resource for solving a broad range of
biological problems. The silkworm, B. mori produces massive amount of silk proteins during the final
stage of larval development. These proteins are stored in the middle silk gland and they are discharged
through the anterior duct and spinneret, at the end of the fifth instar. Two kinds of silk proteins have been
distinguished as major components of silk cocoons, the first being fibroin, a fibrous protein composed of
heavy (H) chain, Light (L) chain and glycoprotein linked by disulfide bonds and the second being sericin a
natural macromolecular protein, serving as an adhesive to unite fibroin for making silk cocoons of
silkworm, B. mori. Recently, silkworm is being used as biofactory for the production of useful protein
using the silk gland, which has promoted the technological development in sericulture. With the above
background silkworm can be classified as a value added biomaterial for medical application, application
of silk protein fibroin and sericin as a biomaterial and other seri-byproducts. The present paper overviews
some important studies carried out on sericin and fibroin of silkworm, Bombyx mori Linn
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ABSTRACT
The domesticated silkworm, Bombyx mori Linn., a lepidopteran molecular model and an important
economic insect that are emerging as an ideal molecular genetic resource for solving a broad range of
biological problems. The silkworm, B. mori produces massive amount of silk proteins during the final
stage of larval development.โปรตีนเหล่านี้จะถูกเก็บไว้ในกลางไหมต่อมและพวกเขาจะปลด
ผ่านท่อด้านหน้าและสปินเนอเร็ต ที่จุดสิ้นสุดของระยะที่ 5 สองชนิดของโปรตีนไหมเป็นส่วนประกอบหลักมี
โดดเด่นของผ้าไหมดักแด้ ครั้งแรกมีไฟโบรอิน เป็นเส้นใยโปรตีนประกอบด้วย
หนัก ( H ) , โซ่ความสว่าง ( L ) โซ่และไกลโคโปรตีนที่เชื่อมโยงพันธบัตรซัลไฟด์และสองเป็นโปรตีนเป็นโปรตีนธรรมชาติ macromolecular
บริการเป็นกาวสมานไฟโบรอินสำหรับทำผ้าไหมดักแด้ของตัวไหม
, B . โมริ เมื่อเร็ว ๆ นี้ไหม ถูกใช้เป็น biofactory สำหรับการผลิตโปรตีนที่มีประโยชน์ใช้ไหม
ต่อม ซึ่งมีการส่งเสริมการพัฒนาเทคโนโลยีด้านหม่อนไหม กับข้างบน
background silkworm can be classified as a value added biomaterial for medical application, application
of silk protein fibroin and sericin as a biomaterial and other seri-byproducts. The present paper overviews
some important studies carried out on sericin and fibroin of silkworm, Bombyx mori Linn
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