Carcinogenesis is a multistep process, and oxidative damage is
linked to the formation of tumors through severalmechanisms. Natural
products derived fromdifferent plants contain awide variety of secondary
metabolites with antioxidant activities that are capable of halting
various steps involved in the development of cancer (Rajput and
Mandal, 2012). It is a fact that a single assay cannot represent the behavior
of free radicals and antioxidants in a living system. Therefore, we
performed an array of assays in the present study (i.e., DPPH, ABTS,
and FRAP models) to investigate the oxidant scavenging potential of
EOs. Our findings indicated good antioxidant activity of EOs in the
FRAP model with a value of 359.11 ± 2.28 nmol Fe+2 Eq/mg extract
and moderate activity in the DPPH and ABTS models with IC50 values
of 47.01 ± 2.42 and 75.90 ± 2.29 μg/mL, respectively, indicating that
the pharmacological effects of EOsmight be due to multiple antioxidant
mechanisms. The results of our DPPH assay are consistent with other
studies in which polar extracts and the polar fractions of I. verum
showed almost the same IC50 values (Yang et al., 20