As the main active constituent of Andrographis paniculata that was applied in treatment of many diseases including inflammation
in ancient China, andrographolide (ANDRO) was found to facilitate reduction of edema and analgesia in arthritis. This suggested
that ANDRO may be promising anti-inflammatory agent to relieve destruction and degeneration of cartilage after inflammation.
In this study, the effect of ANDRO on rabbit articular chondrocytes in vitro was investigated. Results showed that not more than
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